The Second Shot

 https://sashalatypova.substack.com/p/the-second-shot-or-what-do-vaccinators

You notice that [Charles] Richet talks about the “second injection”. This refers to the nature of anaphylaxis: the first interaction with an injected toxin may be not even noticed, be well tolerated or may be at worst mildly irritating. After a period of 2-3 weeks, the second exposure, however, may become very dangerous or fatal. The second exposure in most of Richet’s experiments was by injection. However, with high enough sensitization by the first injection, the anaphylaxis could also result from environmental exposure or ingestion, depending on the degree of sensitization to the “allergen”, or “toxigen” as he termed it.